Association of Plasma Levels of Tumor Necrosis Factor (TNF)–α and Its Soluble Receptors, Two Polymorphisms of the TNF Gene, with Acute Severe Pancreatitis and Early Septic Shock Due to It

Abstract

The study found no association between ASP and the two polymorphisms examined, although some associations were found between TNF2 and TNFB2 alleles with the development of early septic shock in ASP. Plasma level of TNF-alpha or sTNFR was of little value in predicting the occurrence of early septic shock in ASP.