Evidence of increased dopamine receptor signaling in food-restricted rats

Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter

Bruno Giros, Mohamed Jaber, Sara R. Jones et al. · Nature · 1996 · 2.5K citations

Life Sciences, Neuroscience, Pharmacology +12

cAMP Activates MAP Kinase and Elk-1 through a B-Raf- and Rap1-Dependent Pathway

Mark Vossler, Hong Yao, Randall D. York et al. · Cell · 1997 · 1.1K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11

Amphetamine and cocaine induce drug-specific activation of the c-fos gene in striosome-matrix compartments and limbic subdivisions of the striatum.

Ann M. Graybiel, Rosario Moratalla, H.A. Robertson · Proceedings of the National Academy of Sciences · 1990 · 962 citations

Medicine, Neuroscience, Pharmacology +17

Intravenous cocaine, morphine, and amphetamine preferentially increase extracellular dopamine in the "shell" as compared with the "core" of the rat nucleus accumbens.

Francesco E. Pontieri, Gianluigi Tanda, G. Di Chiara · Proceedings of the National Academy of Sciences · 1995 · 868 citations

Medicine, Neuroscience, Pharmacology +17

Tolerance and sensitization to the behavioral effects of drugs

Jane Stewart, Aldo Badiani · Behavioural Pharmacology · 1993 · 595 citations

Medicine, Behavioral Sciences, Psychology +14