Transport of nerve growth factor encapsulated into liposomes across the blood–brain barrier: In vitro and in vivo studies

Procedure for preparation of liposomes with large internal aqueous space and high capture by reverse-phase evaporation.

F Szoka, Demetrios Papahadjopoulos · Proceedings of the National Academy of Sciences · 1978 · 2.3K citations · Full text

Natural Sciences, Biochemistry, Biophysics +16

Amphipathic polyethyleneglycols effectively prolong the circulation time of liposomes

Alexander L. Klibanov, Kazuo Maruyama, Vladimir P. Torchilin et al. · FEBS Letters · 1990 · 2K citations · Full text

Pharmacy, Pharmaceutics, Pharmacokinetics +17

Brain drug delivery of small molecules using immunoliposomes

Jörg Huwyler, Dafang Wu, William M. Pardridge · Proceedings of the National Academy of Sciences · 1996 · 650 citations

Pharmacy, Pharmaceutics, Pharmacology +17

Permeability at the blood-brain and blood-nerve barriers of the neurotrophic factors: NGF, CNTF, NT-3, BDNF

Joseph F. Poduslo, Geoffrey L. Curran · Molecular Brain Research · 1996 · 608 citations

Medicine, Neurobiology, Neuroscience +14

Influence of surface hydrophilicity of liposomes on their interaction with plasma protein and clearance from the circulation: Studies with poly(ethylene glycol)-coated vesicles

Judith Senior, Cristina Delgado, Derek Fisher et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1991 · 521 citations

Life Sciences, Biophysics, Pharmacokinetics +16