A comprehensive picture of non‐site specific oxidation of methionine residues by peroxides in protein pharmaceuticals

The interpretation of protein structures: Estimation of static accessibility

B. Lee, F.M. Richards · Journal of Molecular Biology · 1971 · 5.9K citations

Life Sciences, Biochemistry, Biophysics +12

Methionine residues as endogenous antioxidants in proteins

Rodney L. Levine, Laurent Mosoni, Barbara S. Berlett et al. · Proceedings of the National Academy of Sciences · 1996 · 1K citations

Life Sciences, Biochemistry, Enzymology +15

The development of stable protein formulations: a close look at protein aggregation, deamidation, and oxidation.

Jeffrey L. Cleland, Melissa Powell, S J Shire · PubMed · 1993 · 542 citations

Pharmacy, Biochemistry, Pharmaceutics +17

Chemical instability of protein pharmaceuticals: Mechanisms of oxidation and strategies for stabilization

Shihong Li, Christian Schöneich, Ronald T. Borchardt · Biotechnology and Bioengineering · 1995 · 297 citations

Life Sciences, Biochemistry, Mechanisms Of Toxicity +15

Oxidative modification of glutamine synthetase. II. Characterization of the ascorbate model system.

Rodney L. Levine · Journal of Biological Chemistry · 1983 · 268 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17