To Probe the Origin of Activation Effect of Carboxylic Acid and (+)-NLE in Tridentated Titanium Catalyst Systems

Abstract

The activation effect of carboxylic acid and positive nonlinear effect ((+)-NLE) in tridentated titanium catalyst systems for hetero Diels-Alder reaction and aldol-type reactions has been first elucidated on the basis of X-ray crystal structural analysis of homochiral (pseudo-octahedral coordination geometry with C2 symmetry) and heterochiral (pseudo-octahedral coordination geometry with C1 symmetry) titanium complexes and the observation of their different reactivities with carboxylic acid additive.