Concepedia

Publication | Open Access

STAT3-Activated GM-CSFRα Translocates to the Nucleus and Protects CLL Cells from Apoptosis

DOIFull Paper Access

17

Citations

37

References

2014

Year

Ping Li, David Harris, Zhiming Liu, Uri Rozovski, Alessandra Ferrajoli, Yong-Tao Wang, Carlos E. Bueso‐Ramos, Inbal Hazan‐Halevy, Srđana Grgurević, William G. Wierda,
Molecular Cancer Research

Abstract

Constitutively, activation of STAT3 induces the expression of GM-CSFRα that protects CLL cells from apoptosis, suggesting that inhibition of STAT3 or GM-CSFRα may benefit patients with CLL.

References

YearCitations

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