Factors associated with blood pressure changes in patients receiving diclofenac or etoricoxib: results from the MEDAL study

Abstract

History of hypertension and age at least 65 years were most strongly associated with increased BP. Treatment with etoricoxib vs. diclofenac was also a significant factor for increased BP. CCBs appear to maintain antihypertensive effects with concurrent NSAID therapy better than other examined antihypertensive drug classes.