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Effect of Microbial Antigens on Irradiation Mortality in Mice.
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1959
Year
ImmunodeficienciesRadiation EffectImmunologyRadiation ExposureImmunodominanceEscherichia ColiImmune SystemRadiation BiologyRadiation MedicineInfection ControlVaccinologyVaccine DevelopmentMedicineHumoral ImmunityT Cell ImmunityImmune FunctionClinical MicrobiologyVaccinationIrradiation MortalityPathogenesisTyphoid-paratyphoid VaccineVaccine DesignPrecision VaccinologyVaccine ResearchProteus Morganii
Mortality is reduced by approximately 50% in mice injected with zymosan (1000 γ) or with thermostable antigens from Proteus morganii, Klebsiella pneumoniae, or Escherichia coli. Soluble antigens from Gram-positive organisms, however, are ineffective. The greatest reduction of mortality is obtained by means of a Typhoid-Paratyphoid vaccine.