A Simple Method for the Determination of Glomerular Filtration Rate

Abstract

In 74 adult patients suffering from various renal diseases, the total [51Cr]EDTA plasma clearance (Cl) was compared to the [51Cr]EDTA clearance obtained on assuming a one-pool system (Cl1). Cl1 always exceeded Cl, and the relative difference increased with increasing clearance values. An equation for correction is given. The method for determining Cl1 is very simple and suitable for clinical routine examinations.