Graphene oxide based multilayer capsules with unique permeability properties: facile encapsulation of multiple drugs

Abstract

Novel composite graphene oxide (GO)/poly(allylamine hydrochloride) (PAH) multilayer capsules have been fabricated by layer-by-layer (LbL) assembly. They were found to possess unique permeability properties compared to traditional LbL capsules. These hybrid capsules showed special "core-shell" loading property for encapsulation of dual drugs simultaneously into the core and shell of the capsules respectively.