Serum 2-Hydroxyglutarate Production in <i>IDH1</i>- and <i>IDH2</i>-Mutated De Novo Acute Myeloid Leukemia: A Study by the Acute Leukemia French Association Group

Abstract

Serum 2-HG is a predictor of the presence of IDH1/2 mutations and outcome in these patients. Discrimination between D/L stereoisomers improved specificity.