Allergy and Asthma Proceedings · 1989 · 14 citations · 0 references
Life SciencesImmunologyPharmacotherapyAllergyHypersensitivityImmunotherapyAllergic ConditionsAllergic DiseaseAllergic Disease PathologyAllergic RhinitisAllergic Rhinitis PharmacotherapyAnaphylaxisAllergen-induced Histamine ReleaseAllergic Rhinitis ImmunotherapyAllergic Rhinitis PathologyCromolyn Sodium TherapyHistamine Release AssaysHistamine Release MeasurementNasal Symptom ScoringTopical Steroid Therapy
The nasal surface basophilic metachromatic cells increase in allergic rhinitis and play an important role in the manifestation of nasal symptom. Their numbers were decreased in good correlation with the severity of symptom and nasal provocation reaction after clinical treatment with specific immunotherapy or topical steroid, beclomethasone dipropionate. The percentages of allergen induced histamine release from these cells were not changed after clinical treatment with cromolyn sodium.