High prevalence of <scp>NMDA</scp> receptor IgA/IgM antibodies in different dementia types

Abstract

Serum IgA/IgM NMDAR antibodies occur in a significant number of patients with dementia. Whether these antibodies result from or contribute to the neurodegenerative disorder remains unknown, but our findings reveal a subgroup of patients with high antibody levels who can potentially benefit from immunotherapy.