Inter- and intra-batch variability in the handling characteristics and viscosity of commonly used antibiotic-loaded bone cements

Abstract

Our results suggest that in clinical practice, extrinsic factors such as preparation conditions and methods probably play a more important role than the intrinsic variability of cements. However, variability in handling and viscosity will exist in all brands of cement prepared under theater conditions and the surgeon must be aware of why they may act differently.