Quantification of Liver Iron Overload by T2 Quantitative Magnetic Resonance Imaging in Thalassemia

Abstract

Liver T2 values were found to be more accurate than serum ferritin in predicting liver iron overload and were not influenced by the presence of chronic hepatitis C. Therefore, MRI could serve as a noninvasive alternative to liver biopsy for the quantification of hemosiderosis in HCV+ patients with thalassemia.