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Therapeutic polo-like kinase 1 inhibition results in mitotic arrest and subsequent cell death of blasts in the bone marrow of AML patients and has similar effects in non-neoplastic cell lines

Hematological MalignancyCell DivisionMedicineMixed-phenotype Acute LeukemiaMalignant Blood DisorderAml PatientsMyeloid NeoplasiaCell DeathBone MarrowCell ProliferationMitotic ArrestCell BiologyOncologyRadiation OncologyCancer ResearchHealth Sciences