Functional adaptation to mechanical loading in both cortical and cancellous bone is controlled locally and is confined to the loaded bones

Bone “mass” and the “mechanostat”: A proposal

Harold M. Frost · The Anatomical Record · 1987 · 2.1K citations

Mechanical Stimulation of Bone in Vivo Reduces Osteocyte Expression of Sost/Sclerostin

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Sclerostin, Engineering, Ulnar Cortex +21

Low mechanical signals strengthen long bones

Clinton T. Rubin, A. Simon Turner, Steven D. Bain et al. · Nature · 2001 · 713 citations

Low Mechanical Signals, Biomechanics, Bone Homeostasis +5

Wnt/β-Catenin Signaling Is a Normal Physiological Response to Mechanical Loading in Bone

John A. Robinson, Moitreyee Chatterjee‐Kishore, Paul J. Yaworsky et al. · Journal of Biological Chemistry · 2006 · 495 citations

Mechanobiology, Engineering, Orthopaedic Surgery +10

Mechanical loading thresholds for lamellar and woven bone formation

Charles H. Turner, Mark R. Forwood, J. Y. Rho et al. · Journal of Bone and Mineral Research · 1994 · 474 citations