Angiotensin II Blockade Augments Renal Cortical Microvascular pO<sub>2</sub> Indicating a Novel, Potentially Renoprotective Action

Abstract

These studies indicate that blockade of AII raises pO(2 )in the interstitial microvascular compartment of the normal rat kidney. This effect may contribute to the renoprotective action of ACE inhibitors and AII receptor antagonists in slowing the progression of chronic renal diseases.