Increased Expression of Inducible Nitric Oxide Synthase in Nasal Epithelial Cells in Patients With Allergic Rhinitis

Abstract

We assume that the increased iNOS expression of the epithelial cells in the house dust group might result from stimulated secretion of proinflammatory cytokines during allergic responses. This further suggests profound contribution of nasal epithelial cells to modifying the airway clearance through the production of high levels of NO.