Publication | Open Access
Novel Antitumor Sesquiterpenoids in Achillea millefolium.
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1994
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Medicinal ChemistryBiochemistryNatural SciencesMethyl EstersNew Antitumor SesquiterpenoidsSecondary MetaboliteP-388 Leukemia CellsPhytochemicalNovel Antitumor SesquiterpenoidsPhytochemistryPharmacologyNatural Product Synthesis
Three new antitumor sesquiterpenoids, achimillic acids A, B and C, were isolated as methyl esters from Achillea millefolium and their structures were determined spectroscopically. The compounds were found to be active against mouse P-388 leukemia cells in vivo.
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