Planta Medica · 1982 · 107 citations · 0 references
Life SciencesMicrobiologyDrug DiscoveryMycologyStructure-activity RelationshipsAromatic PlantsStructure-activity Relationship AnalysisAntimicrobial PropertiesMass Spectral Data Analysis
Kolanone, a novel polyisoprenyl benzophenone, has been isolated from the fruit pulp of Garcinia kola HEKKEL. A tentative structure for kolanone has been proposed based on a comparison of its spectral data with that published for other compounds of this class. Kolanone has been shown to exhibit significant antimicrobial activity against a range of organisms.