Enhancement of morphine analgesia and prevention of morphine tolerance in the rat by the cholecystokinin antagonist L-364,718

New peptide in the vertebrate CNS reacting with antigastrin antibodies

J.J. Vanderhaeghen, J. C. SIGNEAU, W Gepts · Nature · 1975 · 759 citations

Life Sciences, Neurobiology, Neuroscience +14

Evidence for the Neuropeptide Cholecystokinin as an Antagonist of Opiate Analgesia

Patricia L. Faris, Barry R. Komisaruk, Linda R. Watkins et al. · Science · 1983 · 582 citations

Medicine, Neuroscience, Pharmacology +17

Biochemical and pharmacological characterization of an extremely potent and selective nonpeptide cholecystokinin antagonist.

Robert S. Chang, Victor J. Lotti · Proceedings of the National Academy of Sciences · 1986 · 542 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Autoradiographic localization and biochemical characterization of peripheral type CCK receptors in rat CNS using highly selective nonpeptide CCK antagonists

DR Hill, NJ Campbell, T.M. Shaw et al. · Journal of Neuroscience · 1987 · 344 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Design of potent, orally effective, nonpeptidal antagonists of the peptide hormone cholecystokinin.

B. Evans, Mark G. Bock, Kenneth E. Rittle et al. · Proceedings of the National Academy of Sciences · 1986 · 328 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16