<i>In Vitro</i> Modulation of Protective Antibody Responses by Estrogen, Progesterone and Interleukin‐6

Abstract

In cells expressing both ER and PR, we could demonstrate that steroids participate in humoral immune responses by modulating asymmetric antibody synthesis. IL-6 proved to be only partially involved. Other possible mechanisms involved in the effect of Pg on blocking antibody responses and their contribution to a successful pregnancy are discussed in the paper.