Design, synthesis and characterization of a novel class of coumarin-based inhibitors of inducible nitric oxide synthase

Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme.

David S. Bredt, Solomon H. Snyder · Proceedings of the National Academy of Sciences · 1990 · 3.3K citations

Life Sciences, Biochemistry, Cell Biology +13

The pharmacological basis of therapeutics

Arthur L. Frank · Environmental Research · 1981 · 2.7K citations

Medicine, Pharmacology, Pharmacotherapy +10

Characterization of three inhibitors of endothelial nitric oxide synthase <i>in vitro</i> and <i>in vivo</i>

Daryl D. Rees, Richard Palmer, Richard Schulz et al. · British Journal of Pharmacology · 1990 · 1.9K citations · Full text

Medicine, Cardiology, Pharmacology +12

The Pharmacological Basis of Therapeutics

Alfred G. Gilman · Optometry and Vision Science · 1976 · 1.3K citations

Medicine, Pharmacology, Pharmacotherapy +10

Delayed Reduction of Ischemic Brain Injury and Neurological Deficits in Mice Lacking the Inducible Nitric Oxide Synthase Gene

Costantino Iadecola, Fangyi Zhang, Robyn Casey et al. · Journal of Neuroscience · 1997 · 670 citations · Full text

Life Sciences, Neurobiology, Neuroscience +15