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<scp>gemini:</scp> software for testing the effects of genotyping errors and multitubes approach for individual identification
133
Citations
19
References
2002
Year
Genetic TestingGeneticsGenomicsGenomic SelectionFalse AlleleGenetic MedicineClinical GeneticsGenetic AnalysisGenotype-phenotype AssociationMolecular EcologyBiostatisticsPublic HealthMolecular DiagnosticsQuantitative GeneticsIndividual GenotypesStatistical GeneticsAneuploidyMultitubes ApproachGenetic VariationPopulation GeneticsIndividual IdentificationPopulation GenomicsMedicine
Abstract Improvements in the determination of individual genotypes from samples with low DNA quantity and quality are of prime importance in molecular ecology and conservation for reliable genetic individual identification (molecular tagging using microsatllites loci). Thus, errors (e.g. allelic dropout and false allele) appearing during samples genotyping must be monitored and eliminated as far as possible. The multitubes approach is a very effective but a costly and time‐consuming solution. In this paper, we present a simulation software that allows evaluation of the effect of genotyping errors on genetic identification of individuals and the effectiveness of a multitubes approach to correct these errors.
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