Mutation of TRPM6 causes familial hypomagnesemia with secondary hypocalcemia

Gitelman's variant of Barter's syndrome, inherited hypokalaemic alkalosis, is caused by mutations in the thiazide-sensitive Na–Cl cotransporter

David B. Simon, Carol Nelson‐Williams, Margaret J. Bia et al. · Nature Genetics · 1996 · 1.2K citations

Life Sciences, Genetics, Human Genetics +2

Paracellin-1, a Renal Tight Junction Protein Required for Paracellular Mg ²⁺ Resorption

David B. Simon, Yin Lu, Keith A. Choate et al. · Science · 1999 · 1.1K citations

Life Sciences, Cell Biology, Physiology +17

LTRPC7 is a Mg·ATP-regulated divalent cation channel required for cell viability

Monica J. S. Nadler, Meredith C. Hermosura, Kazunori Inabe et al. · Nature · 2001 · 931 citations

Life Sciences, Biochemistry, Cell Biology +11

Hypomagnesemia with secondary hypocalcemia is caused by mutations in TRPM6, a new member of the TRPM gene family

Karl P. Schlingmann, Stefanie Weber, Melanie Peters et al. · Nature Genetics · 2002 · 784 citations

Life Sciences, Genetics, Molecular Genetics +11

TRP-PLIK, a Bifunctional Protein with Kinase and Ion Channel Activities

Loren W. Runnels, Lixia Yue, David E. Clapham · Science · 2001 · 733 citations

Life Sciences, Biochemistry, Molecular Biology +17