Dynamic changes in pro- and anti-inflammatory cytokines in microglia after PPAR-γ agonist neuroprotective treatment in the MPTPp mouse model of progressive Parkinson's disease

Macrophage-specific PPARγ controls alternative activation and improves insulin resistance

Justin I. Odegaard, Roberto R. Ricardo-González, Matthew H. Goforth et al. · Nature · 2007 · 2.1K citations · Full text

Life Sciences, Endocrinology, Molecular Biology +15

PPARγ Promotes Monocyte/Macrophage Differentiation and Uptake of Oxidized LDL

Peter Tontonoz, László Nagy, Jacqueline G. Alvarez et al. · Cell · 1998 · 1.8K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Mutant presenilins specifically elevate the levels of the 42 residue β-amyloid peptide in vivo: evidence for augmentation of a 42-specific γ secretase

Joanna L. Jankowsky, Daniel J. Fadale, Jeffrey C. Anderson et al. · Human Molecular Genetics · 2003 · 1.6K citations · Full text

Life Sciences, Neurology, Neuroscience +16

In vivo imaging of microglial activation with [11C](R)-PK11195 PET in idiopathic Parkinson's disease

Alexander Gerhard, Nicola Pavese, Gary Hotton et al. · Neurobiology of Disease · 2005 · 1.2K citations · Full text

Medicine, Neurology, Neuroscience +15

Interleukin-1β, interleukin-6, epidermal growth factor and transforming growth factor-α are elevated in the brain from parkinsonian patients

Makio Mogi, Minoru Harada, Tomoyshi Kondo et al. · Neuroscience Letters · 1994 · 860 citations

Life Sciences, Neurology, Neuroscience +13