Studies on phenothiazines. Part 7. Synthesis of 3‐substituted 2‐aminobenzenethiols and their conversion into phenothiazines

Abstract

Abstract Synthesis of substituted 1‐nitrophenothiazines is reported by the Smiles rearrangement in situ , which involves condensation of 3‐chloro or methyl‐2‐aminobenzenethiol with o ‐halonitrobenzenes (2,4,6‐trinitochloro‐benzene, 1,4‐dichloro‐2,6‐dinitrobenzene, 2,4,6‐tribromo‐1,3‐dinitrobenzene) in the presence of ethanolic sodium hydroxide. Ir and mass spectral studies are included.