Cloning and analysis of the 5′ portion of the human type-III procollagen gene (COL3A1)

DNA sequencing with chain-terminating inhibitors

Frederick Sanger, S. Nicklen, Alan Coulson · Proceedings of the National Academy of Sciences · 1977 · 69.3K citations · Full text

Life Sciences, Microbiology, Molecular Biology +10

The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers

Jeffrey Vieira, Joachim Messing · Gene · 1982 · 6.1K citations

Life Sciences, Genetics, Molecular Biology +15

The isolation of structural genes from libraries of eucaryotic DNA

Tom Maniatis, Ross C. Hardison, Elizabeth Lacy et al. · Cell · 1978 · 1.9K citations

Life Sciences, Genetics, Molecular Biology +11

Charon Phages: Safer Derivatives of Bacteriophage Lambda for DNA Cloning

Frederick R. Blattner, Bill G. Williams, Ann E. Blechl et al. · Science · 1977 · 930 citations

Life Sciences, Biotechnology, Microbiology +15

Spliced early mRNAs of simian virus 40

Arnold Berk, Phillip A. Sharp · Proceedings of the National Academy of Sciences · 1978 · 803 citations · Full text

Life Sciences, Microbiology, Molecular Biology +16