Stereoselective Anti Aldol Reactions of Erythrulose Derivatives. Functionalized Chiral <i>d</i>³ and <i>d</i>⁴ Synthons

Abstract

An improved procedure for the synthesis of anti aldols from protected erythrulose derivatives is reported. The preparation of functionalized d3 and d4 synthons with various stereochemical arrays by means of this methodology is described and subsequently applied to a stereoselective formal synthesis of the natural metabolite goniothalesdiol.