Kappa opioid receptor stimulation decreases amphetamine-induced behavior and neuropeptide mRNA expression in the striatum

Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter

Bruno Giros, Mohamed Jaber, Sara R. Jones et al. · Nature · 1996 · 2.5K citations

Life Sciences, Neuroscience, Pharmacology +12

Opposing tonically active endogenous opioid systems modulate the mesolimbic dopaminergic pathway.

Rainer Spanagel, A. Herz, Toni S. Shippenberg · Proceedings of the National Academy of Sciences · 1992 · 1K citations

Life Sciences, Neuroscience, Pharmacology +16

Opposite effects of mu and kappa opiate agonists on dopamine release in the nucleus accumbens and in the dorsal caudate of freely moving rats.

G. Di Chiara, Assunta Impérato · Journal of Pharmacology and Experimental Therapeutics · 1988 · 922 citations

Medicine, Neuroscience, Pharmacology +17

Mu, delta, and kappa opioid receptor mRNA expression in the rat CNS: An in situ hybridization study

Alfred Mansour, Charles A. Fox, Sharon Burke et al. · The Journal of Comparative Neurology · 1994 · 868 citations · Full text

Life Sciences, Neurobiology, Neuroscience +9

D1 and D2 dopamine receptor function in the striatum: coactivation of D1- and D2-dopamine receptors on separate populations of neurons results in potentiated immediate early gene response in D1-containing neurons

C R Gerfen, KA Keefe · Journal of Neuroscience · 1995 · 284 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17