Journal of Korean Medical Science · 1998 · 41 citations · 0 references
MedicineNeurologyNeuroscienceGlial BiologyNeuropathologyNeuroradiologyAstrocyte BiologyBrain Energy MetabolismDemyelinating DiseasesDemyelinating DisordersGlial MetabolismGlial PathologyCentral Pontine MyelinolysisDemyelinating Lesion PathologyDisease-associated AstrocytesGlial Proliferation In DemyelinationGlucose Metabolism DisordersGlucose Metabolism ImagingMetabolic EncephalopathyNeuroimaging Of Metabolic Disorders
We report a 63 year-old woman who developed central pontine and extrapontine myelinolysis after rapid correction of hyponatremia. Lesions on brain MRI showed hypermetabolism on 18FDG-PET scan in the early stage of the disease and became hypometabolic on the follow-up scan. We suggest that active microglia and astrocytes are the main cause of the increased glucose metabolism.