Concepedia

Characterization of novel germline c-kit gene mutation, KIT-Tyr553Cys, observed in a family with multiple gastrointestinal stromal tumors

Mayumi Nakai, Yuka Hashikura, Mizuka Ohkouchi, Masahiro Yamamura, Takashi Akiyama, Kazuhiro Shiba, Noriko Kajimoto, Yoshitane Tsukamoto, Hiroyuki Hao, Koji Isozaki,

Laboratory Investigation · 2011 · 13 citations · 50 references

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References

50

Gain-of-Function Mutations of c- <i>kit</i> in Human Gastrointestinal Stromal Tumors

Seiichi Hirota, Koji Isozaki, Y Moriyama et al. · Science · 1998 · 4.5K citations

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Efficacy and Safety of Imatinib Mesylate in Advanced Gastrointestinal Stromal Tumors

George D. Demetri, Margaret von Mehren, Charles D. Blanke et al. · New England Journal of Medicine · 2002 · 4.4K citations · Full text

, , +14

Kinase Mutations and Imatinib Response in Patients With Metastatic Gastrointestinal Stromal Tumor

Michael C. Heinrich, Christopher L. Corless, George D. Demetri et al. · Journal of Clinical Oncology · 2003 · 2.3K citations

, , +17

Human proto‐oncogene c‐kit: a new cell surface receptor tyrosine kinase for an unidentified ligand.

Yosef Yarden, Wun-Jing Kuang, Teresa L. Yang‐Feng et al. · The EMBO Journal · 1987 · 1.6K citations · Full text

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Somatic Activation of KIT in Distinct Subtypes of Melanoma

John A. Curtin, Klaus J. Busam, Daniel Pinkel et al. · Journal of Clinical Oncology · 2006 · 1.6K citations · Full text

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