Small intestinal permeability is increased in diarrhoea predominant <scp>IBS</scp>, while alterations in gastroduodenal permeability in all <scp>IBS</scp> subtypes are largely attributable to confounders

Abstract

Small intestinal permeability is increased in patients with IBS-D compared to healthy controls, irrespective of confounding factors. Adjustment for confounders is necessary when studying intestinal permeability, especially in a heterogeneous disorder such as IBS.