Synthesis of the individual, pharmacologically distinct, enantiomers of a tetrahydrocannabinol derivative

.alpha.-Methoxy-.alpha.-trifluoromethylphenylacetic acid, a versatile reagent for the determination of enantiomeric composition of alcohols and amines

James A. Dale, David L. Dull, Harry S. Mosher · The Journal of Organic Chemistry · 1969 · 2.5K citations

Natural Sciences, Chemistry, Analytical Chemistry +6

Enantiomeric cannabinoids: stereospecificity of psychotropic activity

Raphael Mechoulam, J. J. Feigenbaum, N. Lander et al. · Cellular and Molecular Life Sciences · 1988 · 208 citations

Medicine, Medicinal Chemistry, Pharmacology +8

Nonpsychotropic cannabinoid acts as a functional N-methyl-D-aspartate receptor blocker.

J. J. Feigenbaum, Felix Bergmann, Saul A. Richmond et al. · Proceedings of the National Academy of Sciences · 1989 · 183 citations · Full text

Medicine, Neuroscience, Pharmacology +15

Stereochemical effects of 11-OH-Δ8-tetrahydrocannabinol-dimethylheptyl to inhibit adenylate cyclase and bind to the cannabinoid receptor

A­llyn C. Howlett, Thierry Champion, Gerald H. Wilken et al. · Neuropharmacology · 1990 · 122 citations

Medicine, Medicinal Chemistry, Pharmacology +14

Stereochemical effects of 11-OH-Δ8-THC-dimethylheptyl in mice and dogs

Patrick Little, Raphael Mechoulam, Billy R. Martin · Pharmacology Biochemistry and Behavior · 1989 · 109 citations

Medicine, Medicinal Chemistry, Pharmacology +7