Concepedia

Mutations of FLT3/ITD confer resistance to multiple tyrosine kinase inhibitors

Allen B. Williams, Bao Nguyen, L Li, Patrick A. Brown, Mark J. Levis, Daniel J. Leahy, Donald Small

Leukemia · 2012 · 113 citations · 45 references

DOI

Concepts

References

45

Efficacy and Safety of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in Chronic Myeloid Leukemia

Brian Druker, Moshe Talpaz, Debra Resta et al. · New England Journal of Medicine · 2001 · 5.2K citations · Full text

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Imatinib Compared with Interferon and Low-Dose Cytarabine for Newly Diagnosed Chronic-Phase Chronic Myeloid Leukemia

Stephen G. O’Brien, François Guilhot, Richard A. Larson et al. · New England Journal of Medicine · 2003 · 3.6K citations · Full text

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MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia

Scott A. Armstrong, Jane Staunton, Lewis B. Silverman et al. · Nature Genetics · 2001 · 1.7K citations

, , +16

Internal tandem duplication of the flt3 gene found in acute myeloid leukemia.

Mitsushige Nakao, S Yokota, Toshiki Iwai et al. · PubMed · 1996 · 1.2K citations

, , +14

Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies

Yukiya Yamamoto · Blood · 2001 · 1.1K citations

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