Anti‐inflammatory and related actions of <i>Syzygium cuminii</i> seed extract

Abstract

Abstract The chloroform fraction of Syzygium cuminii seeds was found to cause significant inhibition of carrageenin, kaolin and other mediator‐induced oedema. The extract inhibited exudation of protein, leakage of dye in peritoneal inflammation and migration of leucocytes. The extract also caused inhibition of grannloma formation, experimental arthritis and also turpentine‐induced joint oedema. Significant anti‐pyretic action of the extract was also observed against yeast‐induced pyrexia. These observations established the anti‐inflammatory effect of S. cuminii seed extract in exudative, proliferative and chronic stages of inflammation along with an anti‐pyretic action.