Reduction of Serum LH and Testosterone in Male Rats by a Partially Purified Bovine Pineal Extract

Abstract

Defattedbovine pineal glands were extracted with acetic acid and further purified on Sephadex G-25 to yield three antigonadotropic fractions designated as F3, F4 and F5.Each of the fractions was administered separately at either 5 or 10 g eq (equivalent to starting wet weight of tissue) dose