Journal of Clinical Microbiology · 2004 · 55 citations · 15 references
Life SciencesInfectious DiseasesMicrobiologyMedical MicrobiologyMolecular VirologyVirologyAnimal VirusesViral ClassificationViral Hemorrhagic FeversViral InfectionsViral ZoonosesVirus ClassificationHantavirus InfectionsHemorrhagic Viral DiseaseHemorrhagic Viral FeversMolecular Species IdentificationReverse Transcription Polymerase Chain Reaction (Rt-pcr)Virus CharacterizationVirus DiseasesVirus Strain Classification
Viral RNA was amplified by reverse transcription-PCR from a patient suffering from hemorrhagic fever with renal syndrome (HFRS) in Germany. The virus strain could be assigned to the Dobrava hantavirus (DOBV). This is the first molecular identification of human infection by DOBV in central Europe and the first proof that a virus strain related to the DOBV-Aa lineage, carried by Apodemus agrarius rodents, is able to cause HFRS.
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