Concepedia

A human oncogene formed by the fusion of truncated tropomyosin and protein tyrosine kinase sequences

Dionisio Martı́n-Zanca, Stephen H. Hughes, Mariano Barbacid

Nature · 1986 · 803 citations · 35 references

Open access

Concepts

MedicineMolecular BiologyOncologyMolecular OncologyOncogenesSignal TransductionOncogene ActivationOncogene AmplificationOncogenic Fusion GenesOncogenic Signaling PathwaysProto-oncogene ActivationReceptor Tyrosine Kinase OncogenesCellular OncogenesKinase Fusion GenesKinase Fusion OncogenesOncogenic Fusion MechanismsOncogenic Fusion ProteinsReceptor Tyrosine Kinase Gene AmplificationTyrosine Kinase Receptors

References

35

Detection of specific sequences among DNA fragments separated by gel electrophoresis

E.M. Southern · Journal of Molecular Biology · 1975 · 32.8K citations

Life Sciences, Molecular Biology, Molecular Genetics +12

Molecular Cloning. A Laboratory Manual

EJ Wood · Biochemical Education · 1983 · 30.6K citations

Life Sciences, Molecular Biology, Molecular Genetics +13

A new technique for the assay of infectivity of human adenovirus 5 DNA

Frank L. Graham, A.J. van der Eb · Virology · 1973 · 9.7K citations

Life Sciences, Infectious Diseases, Molecular Biology +10

A new method for sequencing DNA.

Allan M. Maxam, Wendy V. Gilbert · Proceedings of the National Academy of Sciences · 1977 · 8K citations · Full text

Life Sciences, Biology, Molecular Biology +16

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

A Ullrich, Lisa M. Coussens, Joel S. Hayflick et al. · Nature · 1984 · 2.8K citations

Life Sciences, Genetics, Molecular Biology +7