British Journal of Urology · 1977 · 47 citations · 6 references
MedicinePharmacologyPharmacotherapyBladder ManagementPharmaceutical CareVoiding DysfunctionBenign Prostatic HyperplasiaPressure-flow StudiesControl Group DesignDouble-blind TrialsMatched Control GroupPharmacological TherapyPressure - Flow CharacteristicsProstatic Obstruction
62 patients with benign prostatic hypertrophy, leading to bladder outflow obstruction, took part in a randomised double-blind trial. Those patients in the treatment group took 6 capsules of a polyene macrolide, candicidin, each day (300 mg daily dose). Subjective improvement was noted in both the treated and the control group. This improvement was not confirmed by pressure flow analysis of micturition. The results of this trial do not support the view that candicidin is a useful drug in the treatment of benign prostatic hypertrophy.
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The Cholesterol Content of Normal and Enlarged Prostates
G. I. M. Swyer · Cancer Research · 1942 · 91 citations
Medicine, Endocrinology, Urology +11
Natural history of prostatic obstruction. A prospective survey.
A. A. Craigen, Jennifer Hickling, Connie Saunders et al. · PubMed · 1969 · 65 citations
Effect of candicidin on the human benign hypertrophied prostate gland.
Keshin Jg · PubMed · 1973 · 27 citations
Medicine, Endocrinology, Urology +12
Efficacy of candicidin in benign prostatic hypertrophy
Lazarus A. Orkin · Urology · 1974 · 20 citations