Synthesis and pharmacology of pyrido[2,3-d]pyrimidinediones bearing polar substituents as adenosine receptor antagonists

Comparative pharmacology of human adenosine receptor subtypes – characterization of stably transfected receptors in CHO cells

Karl‐Norbert Klotz, Jutta Hessling, Jutta Hegler et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 1997 · 723 citations · Full text

Medicine, Molecular Biology, Pharmacology +12

Pyrido[2,3-d]pyrimidines. IV. Synthetic studies leading to various oxopyrido[2,3-d]pyrimidines

Arthur D. Broom, Jaewon L. Shim, Gary L. Anderson · The Journal of Organic Chemistry · 1976 · 246 citations

Natural Sciences, Chemistry, Medicinal Chemistry +8

Measurement of guanine nucleotide-binding protein activation by A1 adenosine receptor agonists in bovine brain membranes: stimulation of guanosine-5'-O-(3-[35S]thio)triphosphate binding.

A. Lorenzen, M Fuss, Heidrun Vogt et al. · Molecular Pharmacology · 1993 · 162 citations

Life Sciences, Biochemistry, Pharmacology +14

Multigram-Scale Syntheses, Stability, and Photoreactions of A_2A Adenosine Receptor Antagonists with 8-Styrylxanthine Structure:  Potential Drugs for Parkinson's Disease

Jörg Hockemeyer, Joachim C. Burbiel, Christa E. Müller · The Journal of Organic Chemistry · 2004 · 138 citations

Pharmacy, Medicinal Chemistry, Pharmacology +10

2-Chloro-N6-[3H]cyclopentyladenosine ([3HCCPA) ?a high affinity agonist radioligand for A1 adenosine receptors

Karl‐Norbert Klotz, Martin J. Lohse, Ulrich Schwabe et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 1989 · 128 citations

Medicine, Molecular Biology, Pharmacology +7