IgG4‐positive plasma cells in cutaneous Rosai‐Dorfman disease: an additional immunohistochemical feature and possible relationship to IgG4‐related sclerosing disease

Abstract

The presence of many IgG4+ plasma cells and stromal fibrosis suggests that CRDD may be related to IgG4-related sclerosing disease. Many IgG4+ plasma cells is another feature of CRDD, and serum IgG4 may be elevated.