Concepedia

Publication | Open Access

Protective Role of DNJ-27/ERdj5 in <i>Caenorhabditis elegans</i> Models of Human Neurodegenerative Diseases

DOIFull Paper Access

58

Citations

73

References

2013

Year

Fernando Muñoz-Lobato, María Jesús Rodríguez‐Palero, Francisco José Naranjo-Galindo, Freya Shephard, Christopher Gaffney, Nathaniel J. Szewczyk, Shusei Hamamichi, Kim A. Caldwell, Guy A. Caldwell, Chris D. Link,
Antioxidants and Redox Signaling

Abstract

Our data support a scenario where the levels of DNJ-27/ERdj5 in the ER impact cytoplasmic protein homeostasis and the integrity of the mitochondrial network which might underlie its protective effects in models of proteotoxicity associated to human ND.

References

YearCitations

Page 1