Concepedia

Opioid efficacy is linked to the LiCl-sensitive, inositol-1,4,5-trisphosphate-restorable pathway

Robert B. Raffa, Charlene D. Connelly, Rebecca P. Martinez

European Journal of Pharmacology · 1992 · 20 citations · 7 references

Concepts

MedicinePharmacologyNeuropharmacologyPain MedicinePharmacodynamicsAnalgesiaAnalgesic PharmacologyOpioid AnalgesicsOpioid PharmacologyOpioid TherapyInositol 1, 4, 5-Trisphosphate Receptor SignalingInositol 1, 4, 5-Trisphosphate ReceptorsInositol Trisphosphate SignalingOpioid PharmacodynamicsOpioid Receptor Agonists

References

7

A METHOD FOR DETERMINING LOSS OF PAIN SENSATION

F. E. D'Amour, Donn L. Smith · Journal of Pharmacology and Experimental Therapeutics · 1941 · 3.2K citations

Nursing, Pharmacology, Pain Management +14

The inhibitory effect of fentanyl and other morphine-like analgesics on the warm water induced tail withdrawl reflex in rats.

Patricia A. Janssen, Niemegeers Cj, Dony Jg · PubMed · 1963 · 525 citations

Medicine, Pharmacology, Behavioral Pharmacology +13

Potency of infused spinal antinociceptive agents is inversely related to magnitude of tolerance after continuous infusion.

Craig W. Stevens, Tony L. Yaksh · Journal of Pharmacology and Experimental Therapeutics · 1989 · 126 citations

Medicine, Pharmacology, Neuropharmacology +16

Characteristics of dose-dependent antagonism by beta-funaltrexamine of the antinociceptive effects of intrathecal mu agonists.

Erling Mjanger, Tony L. Yaksh · Journal of Pharmacology and Experimental Therapeutics · 1991 · 74 citations

Medicine, Neuroscience, Pharmacology +17

Potency of Infused Spinal Antinociceptive Agents Is Inversely Related to Magnitude of Tolerance After Continuous Infusion

Craig W. Stevens, Tony L. Yaksh · Survey of Anesthesiology · 1990 · 56 citations

Medicine, Neurosurgery, Pharmacology +14