Prediction of Adverse Outcome with Cerebral Lactate Level and Apparent Diffusion Coefficient in Infants with Perinatal Asphyxia

Abstract

Higher lactate-choline ratios in basal ganglia and thalami of infants with perinatal asphyxia were predictive of worse clinical outcomes. Absolute ADC in the same brain regions did not indicate a statistically significant relationship with clinical outcome. Cerebral lactate level is useful in identifying infants who would benefit from early therapeutic intervention.