Factor VIII requirement to maintain a target plasma level in the prophylactic treatment of severe hemophilia A: influences of variance in pharmacokinetics and treatment regimens

Prophylaxis versus Episodic Treatment to Prevent Joint Disease in Boys with Severe Hemophilia

Marilyn J. Manco‐Johnson, Thomas C. Abshire, Amy D. Shapiro et al. · New England Journal of Medicine · 2007 · 1.9K citations · Full text

Medicine, Hematology, Orthopedic Surgery +13

Twenty‐five years' experience of prophylactic treatment in severe haemophilia A and B

I. M. Nilsson, Erik Berntorp, Thomas Löfqvist et al. · Journal of Internal Medicine · 1992 · 968 citations

Medicine, Hematology, Pediatrics +10

Break‐through bleeding in relation to predicted factor VIII levels in patients receiving prophylactic treatment for severe hemophilia A

P. Collins, Victor S. Blanchette, Kathelijn Fischer et al. · Journal of Thrombosis and Haemostasis · 2008 · 324 citations

Medicine, Hematology, Hemostasis +12

Haemophilia in Sweden VII. Incidence, Treatment and Prophylaxis of Arthropathy and other Musculo-Skeletal Manifestations of Haemophilia A and B

A Ahlberg · Acta Orthopaedica Scandinavica · 1965 · 253 citations · Full text

Medicine, Orthopaedic Surgery, Orthopedic Surgery +10

Prophylactic treatment for severe haemophilia: comparison of an intermediate‐dose to a high‐dose regimen

Kathelijn Fischer, J. Astermark, Johanna G. van der Bom et al. · Haemophilia · 2002 · 156 citations

Medicine, Hematology, Pharmacotherapy +13