Organic & Biomolecular Chemistry · 2011 · 57 citations · 35 references
EngineeringChemistryMolecular BiologyAnalytical ChemistryBiosensorsSensorsBiological SensorsCell-based BiosensorsCell-surface LabelingChemical SensorsMolecular SensorsOptical BiosensorsBiomolecular DetectionChromogenic DetectionFluorescence-based AssaysFluorescent BiosensingFluorescent Dye LabelingFluorescent LabelingFluorescent Molecular SensorsFluorescent Probe Design
A chromogenic and fluorogenic detection of aldehydes was achieved via analyte triggered opening of the deoxylactam of N-(rhodamine B)-deoxylactam-ethylenediamine (dRB-EDA). The utility of the sensor was demonstrated by fluorescent labeling of aldehyde-displaying sialoproteins on cell surfaces.
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Cell Surface Engineering by a Modified Staudinger Reaction
Eliana Saxon, Carolyn R. Bertozzi · Science · 2000 · 2.4K citations
High-efficiency labeling of sialylated glycoproteins on living cells
Ying Zeng, T.N.C. Ramya, Anouk Dirksen et al. · Nature Methods · 2009 · 431 citations · Full text