Bilateral Cryptorchidism Associated with Terminal Deletion of 10q

Abstract

We report on an infant with terminal deletion of 10q (del10q26.11) presenting with bilateral cryptorchidism. Of 9 males previously reported with terminal deletion of 10q, 1 had an intersex phenotype, and the others all had combinations of cryptorchidism, micropenis, and hypospadias. Terminal deletion of 10q appears to include some genes indispensable for normal male genital development.