Concepedia

Solid-Liquid Phase Transfer Catalysis Without Solvent: Further Improvement in S<sub>N</sub>Ar Reactions

André Loupy, Noelle Philippon, P. Pigeon, J. Sansoulet, Hervé Galons

Synthetic Communications · 1990 · 27 citations · 7 references

DOI

Concepts

Abstract

Abstract Solid-liquid PTC without added solvent efficiently promotes SNAr reactions of a variety of anionic nucleophiles generated in situ. This methodology is applied with success to some examples concerning non-activated aromatic systems. TDA-1 is the most effective catalyst.

References

7

Tris(polyoxaalkyl)amines (trident), a new class of solid-liquid phase-transfer catalysts

G Soula · The Journal of Organic Chemistry · 1985 · 114 citations

, , +7

Microwave Irradiation Plus Solid-Liquid Phase Transfer Catalysis Without Solvent: Further Improvement in Anionic Activation

G. Bram, André Loupy, Mustapha Majdoub · Synthetic Communications · 1990 · 49 citations

, , +14

Anionic Activation by Solid—Liquid Phase Transfer Catalysis Without Solvent: An Improvement in Organic Synthesis

G. Bram, A. Loupy, J. Sansoulet · Israel Journal of Chemistry · 1985 · 42 citations

, , +14

N-alkyl-4-(N′,N′-dialkylamino)pyridinium salts: thermally stable phase transfer catalysts for nucleophilic aromatic displacement

Daniel J. Brunelle, Daniel A. Singleton · Tetrahedron Letters · 1984 · 38 citations

, , +11

Nucleophilic aromatic substitution reactions of unactivated aryl chlorides with methoxide ion in hexamethylphosphoramide

James E. Shaw, Dennis C. Kunerth, Steven B. Swanson · The Journal of Organic Chemistry · 1976 · 33 citations

, , +12